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i use to do weed years ago, and have it with a south african succulent called sceletium or kanna takes the edge off cannabis real quick, tried it with people who couldn't smoke it for that reason every time they loved it is an amazing plant you all should check it out, once apon a time it used to be used as currency (you make your mind up how special it is) grows like a weed

newer research shows that dopamine is (when looking at what it does to the psyche; otherwise we're very clear how it is important for movement and why parkinson's disease has the symptoms it has) mainly responsible for motivation. if a substance releases dopamine, it's not necessarily pleasurable but rather something you'll be motivated to repeat. if you're low on dopamine, or on an antipsychotic drug, you won't find motivation and energy to get your ass up and do something. parkinson's patients who take dopamine agonists to make up for the dopamin lost by the disease, can sometimes get uncontrollable urges — some may start a gambling career, others may pursue inappropriate sexual relations. but i know it's not about dopamine. your body produces it's own substances that bind to cannabinoid receptors in the brain. of course there might be individual differences in how sensitive the receptors are or how fast anandamide (the endogenous cannabinoid) is degraded after use, but your brain has gotten used to how it functions for your whole life. it has set a sort of level it considers normal and will try to regulate accordingly if you add substances to throw it off balance. if you're on opioids (or any other addictive drug) all the time you will need them to just feel normal. there are substances that block your cannabinoid receptors, and they are very effective at for losing weight, but they were withdrawn from the market because of the side effects. the prototypical anti-cannabinoid, rimonabant, can cause depression (in at least 10% of the people; 1% of the people who take it even ponder suicide), insomnia, anxiety, nausea, flu-like symptoms, spasms and seizures. it's really not something you'd want to take. also, you can only speculate why you compare your normal state to that of someone else on cannabis. there are hundreds of reasons and we do not yet have the technology to identify the true cause (in most cases) and much less the medicines to counteract the imbalance. the brain is extremely complicated and we're still lighyears away from understanding how it really works. even for "simple" diseases that don't involve the brain, and that are well understood for decades (such as cystic fibrosis, muscular dystrophy or infections with rabies or even herpes) cannot be treated adequately. with the tools we have at hand right now, psychiatry is like trying to put out a fire by either hitting it with a hammer or a wooden stick. so in short: no, it's not advisable to experiment in this direction. there is a possibility to make yourself less susceptible to the effects of cannabis. if you smoke a lot you'll get a tolerance. but i doubt that's effective at what you really want to achieve.